Exploring a causal role of DNA methylation in the relationship between maternal vitamin B(12) during pregnancy and child’s IQ at age 8, cognitive performance and educational attainment: a two-step Mendelian randomization study

An adequate intake of vitamin B(12) during pregnancy plays an important role in offspring neurodevelopment, potentially via epigenetic processes. We used a two-step Mendelian randomization approach to assess whether DNA methylation plays a mediating and causal role in associations between maternal v...

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Detalles Bibliográficos
Autores principales: Caramaschi, Doretta, Sharp, Gemma C., Nohr, Ellen A., Berryman, Katie, Lewis, Sarah J., Davey Smith, George, Relton, Caroline L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703349/
https://www.ncbi.nlm.nih.gov/pubmed/28453778
http://dx.doi.org/10.1093/hmg/ddx164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703349/
https://www.ncbi.nlm.nih.gov/pubmed/28453778
http://dx.doi.org/10.1093/hmg/ddx164

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