Caspase-1 deficiency reduces eosinophilia and interleukin-33 in an asthma exacerbation model

Rhinovirus infections are common triggers of asthma exacerbations. Viruses can activate the inflammasome, resulting in processing and activation of caspase-1. This recruitment triggers production of interleukin (IL)-1β and IL-18, which have been implicated in asthma. Elucidating the involvement of t...

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Detalles Bibliográficos
Autores principales: Menzel, Mandy, Akbarshahi, Hamid, Mahmutovic Persson, Irma, Puthia, Manoj, Bjermer, Leif, Uller, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703353/
https://www.ncbi.nlm.nih.gov/pubmed/29204432
http://dx.doi.org/10.1183/23120541.00047-2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703353/
https://www.ncbi.nlm.nih.gov/pubmed/29204432
http://dx.doi.org/10.1183/23120541.00047-2017

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