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Caspase-1 deficiency reduces eosinophilia and interleukin-33 in an asthma exacerbation model
Rhinovirus infections are common triggers of asthma exacerbations. Viruses can activate the inflammasome, resulting in processing and activation of caspase-1. This recruitment triggers production of interleukin (IL)-1β and IL-18, which have been implicated in asthma. Elucidating the involvement of t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703353/ https://www.ncbi.nlm.nih.gov/pubmed/29204432 http://dx.doi.org/10.1183/23120541.00047-2017 |