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Variables that influence BRAF mutation probability: A next-generation sequencing, non-interventional investigation of BRAFV600 mutation status in melanoma

BACKGROUND: The incidence of melanoma, particularly in older patients, has steadily increased over the past few decades. Activating mutations of BRAF, the majority occurring in BRAFV600, are frequently detected in melanoma; however, the prognostic significance remains unclear. This study aimed to de...

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Detalles Bibliográficos
Autores principales: Gaiser, Maria Rita, Skorokhod, Alexander, Gransheier, Diana, Weide, Benjamin, Koch, Winfried, Schif, Birgit, Enk, Alexander, Garbe, Claus, Bauer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703505/
https://www.ncbi.nlm.nih.gov/pubmed/29176861
http://dx.doi.org/10.1371/journal.pone.0188602