Cargando…

Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift

Targeting metabolism is emerging as a promising therapeutic strategy for modulation of the immune response in human diseases. In the presented study we used the lipopolysaccharide (LPS)-mediated activation of RAW 264.7 macrophage-like cell line as a model to investigate changes in the metabolic phen...

Descripción completa

Detalles Bibliográficos
Autores principales: Scrima, Rosella, Menga, Marta, Pacelli, Consiglia, Agriesti, Francesca, Cela, Olga, Piccoli, Claudia, Cotoia, Antonella, De Gregorio, Alessandra, Gefter, Julia V., Cinnella, Gilda, Capitanio, Nazzareno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703549/
https://www.ncbi.nlm.nih.gov/pubmed/29176872
http://dx.doi.org/10.1371/journal.pone.0188683