Characterizing steady states of genome-scale metabolic networks in continuous cell cultures

In the continuous mode of cell culture, a constant flow carrying fresh media replaces culture fluid, cells, nutrients and secreted metabolites. Here we present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, ta...

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Detalles Bibliográficos
Autores principales: Fernandez-de-Cossio-Diaz, Jorge, Leon, Kalet, Mulet, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703580/
https://www.ncbi.nlm.nih.gov/pubmed/29131817
http://dx.doi.org/10.1371/journal.pcbi.1005835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703580/
https://www.ncbi.nlm.nih.gov/pubmed/29131817
http://dx.doi.org/10.1371/journal.pcbi.1005835

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