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Characterizing steady states of genome-scale metabolic networks in continuous cell cultures
In the continuous mode of cell culture, a constant flow carrying fresh media replaces culture fluid, cells, nutrients and secreted metabolites. Here we present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, ta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703580/ https://www.ncbi.nlm.nih.gov/pubmed/29131817 http://dx.doi.org/10.1371/journal.pcbi.1005835 |