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Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella

Intraflagellar transport (IFT) particles are composed of polyprotein complexes IFT-A and IFT-B as well as cargo adaptors such as the BBSome. Two IFT-B subunits, IFT25 and IFT27 were found to form a heterodimer, which is essential in exporting the BBSome out of the cilium but not involved in flagella...

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Detalles Bibliográficos
Autores principales: Dong, Bin, Wu, Song, Wang, Jing, Liu, Yan-Xia, Peng, Zhao, Meng, De-Mei, Huang, Kaiyao, Wu, Mingfu, Fan, Zhen-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703605/
https://www.ncbi.nlm.nih.gov/pubmed/28838966
http://dx.doi.org/10.1242/bio.026278