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Autophagy promotes degradation of internalized collagen and regulates distribution of focal adhesions to suppress cell adhesion

Adhesion of cells to the extracellular matrix (ECM) via focal adhesions (FAs) is crucial for cell survival, migration, and differentiation. Although the regulation of FAs, including by integrins and the ECM, is important to cell behavior, how FAs are regulated is not well known. Autophagy is induced...

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Detalles Bibliográficos
Autores principales: Kawano, Shinichi, Torisu, Takehiro, Esaki, Motohiro, Torisu, Kumiko, Matsuno, Yuichi, Kitazono, Takanari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703610/
https://www.ncbi.nlm.nih.gov/pubmed/28970230
http://dx.doi.org/10.1242/bio.027458