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F-actin reorganization by V-ATPase inhibition in prostate cancer

The vacuolar ATPase (V-ATPase) proton pump sustains cellular pH homeostasis, and its inhibition triggers numerous stress responses. However, the cellular mechanisms involved remain largely elusive in cancer cells. We studied V-ATPase in the prostate cancer (PCa) cell line PC-3, which has characteris...

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Detalles Bibliográficos
Autores principales: Licon-Munoz, Yamhilette, Michel, Vera, Fordyce, Colleen A., Parra, Karlett J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703614/
https://www.ncbi.nlm.nih.gov/pubmed/29038303
http://dx.doi.org/10.1242/bio.028837