Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

Dysfunction of the oxidative phosphorylation (OXPHOS) system is a major cause of human disease and the cellular consequences are highly complex. Here, we present comparative analyses of mitochondrial proteomes, cellular transcriptomes and targeted metabolomics of five knockout mouse strains deficien...

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Detalles Bibliográficos
Autores principales: Kühl, Inge, Miranda, Maria, Atanassov, Ilian, Kuznetsova, Irina, Hinze, Yvonne, Mourier, Arnaud, Filipovska, Aleksandra, Larsson, Nils-Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703644/
https://www.ncbi.nlm.nih.gov/pubmed/29132502
http://dx.doi.org/10.7554/eLife.30952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703644/
https://www.ncbi.nlm.nih.gov/pubmed/29132502
http://dx.doi.org/10.7554/eLife.30952

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