An adaptation of astronomical image processing enables characterization and functional 3D mapping of individual sites of excitation-contraction coupling in rat cardiac muscle

In beating cardiomyocytes, synchronized localized Ca(2+) transients from thousands of active excitation-contraction coupling sites (ECC couplons) comprising plasma and sarcoplasmic reticulum membrane calcium channels are important determinants of the heart's performance. Nevertheless, our knowl...

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Detalles Bibliográficos
Autores principales: Tian, Qinghai, Kaestner, Lars, Schröder, Laura, Guo, Jia, Lipp, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703646/
https://www.ncbi.nlm.nih.gov/pubmed/29135437
http://dx.doi.org/10.7554/eLife.30425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703646/
https://www.ncbi.nlm.nih.gov/pubmed/29135437
http://dx.doi.org/10.7554/eLife.30425

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