Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4(+) Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression

Sepsis is the dysregulated response of the host to systemic, mostly bacterial infection, and is associated with an enhanced susceptibility to life-threatening opportunistic infections. During polymicrobial sepsis, dendritic cells (DCs) secrete enhanced levels of interleukin (IL) 10 due to an altered...

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Detalles Bibliográficos
Autores principales: Smirnov, Anna, Pohlmann, Stephanie, Nehring, Melanie, Ali, Shafaqat, Mann-Nüttel, Ritu, Scheu, Stefanie, Antoni, Anne-Charlotte, Hansen, Wiebke, Büettner, Manuela, Gardiasch, Miriam J., Westendorf, Astrid M., Wirsdörfer, Florian, Pastille, Eva, Dudda, Marcel, Flohé, Stefanie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703700/
https://www.ncbi.nlm.nih.gov/pubmed/29218051
http://dx.doi.org/10.3389/fimmu.2017.01622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703700/
https://www.ncbi.nlm.nih.gov/pubmed/29218051
http://dx.doi.org/10.3389/fimmu.2017.01622

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