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SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes

Sorting nexin 27 (SNX27) recycles PSD-95, Dlg1, ZO-1 (PDZ) domain-interacting membrane proteins and is essential to sustain adequate brain functions. Here we define a fundamental SNX27 function in T lymphocytes controlling antigen-induced transcriptional activation and metabolic reprogramming. SNX27...

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Detalles Bibliográficos
Autores principales: Tello-Lafoz, M., Rodríguez-Rodríguez, C., Kinna, G., Loo, L. S., Hong, W., Collins, B. M., Teasdale, R. D., Mérida, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703713/
https://www.ncbi.nlm.nih.gov/pubmed/29180720
http://dx.doi.org/10.1038/s41598-017-16370-w