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Calreticulin: Challenges Posed by the Intrinsically Disordered Nature of Calreticulin to the Study of Its Function

Calreticulin is a Ca(2+)-binding chaperone protein, which resides mainly in the endoplasmic reticulum but also found in other cellular compartments including the plasma membrane. In addition to Ca(2+), calreticulin binds and regulates almost all proteins and most of the mRNAs deciding their intracel...

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Detalles Bibliográficos
Autores principales: Varricchio, Lilian, Falchi, Mario, Dall'Ora, Massimiliano, De Benedittis, Caterina, Ruggeri, Alessandra, Uversky, Vladimir N., Migliaccio, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703715/
https://www.ncbi.nlm.nih.gov/pubmed/29218307
http://dx.doi.org/10.3389/fcell.2017.00096