Nav channel binder containing a specific conjugation-site based on a low toxicity β-scorpion toxin

Voltage-gated sodium (Nav) channels play a key role in generating action potentials which leads to physiological signaling in excitable cells. The availability of probes for functional studies of mammalian Nav is limited. Here, by introducing two amino acid substitutions into the beta scorpion toxin...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubota, Tomoya, Dang, Bobo, Carvalho-de-Souza, Joao L., Correa, Ana M., Bezanilla, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703725/
https://www.ncbi.nlm.nih.gov/pubmed/29180755
http://dx.doi.org/10.1038/s41598-017-16426-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703725/
https://www.ncbi.nlm.nih.gov/pubmed/29180755
http://dx.doi.org/10.1038/s41598-017-16426-x

Ejemplares similares