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Nav channel binder containing a specific conjugation-site based on a low toxicity β-scorpion toxin
Voltage-gated sodium (Nav) channels play a key role in generating action potentials which leads to physiological signaling in excitable cells. The availability of probes for functional studies of mammalian Nav is limited. Here, by introducing two amino acid substitutions into the beta scorpion toxin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703725/ https://www.ncbi.nlm.nih.gov/pubmed/29180755 http://dx.doi.org/10.1038/s41598-017-16426-x |