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Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine

Double mutant heat-labile toxin (dmLT) is a promising adjuvant for oral vaccine administration. The aims of our study were to develop sensitive methods to detect low concentrations of dmLT and to use the assays in preformulation studies to determine whether dmLT remains stable under conditions encou...

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Detalles Bibliográficos
Autores principales: White, Jessica A., Haghighi, Candace, Brunner, Johanna, Estrada, Marcus, Lal, Manjari, Chen, Dexiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703769/
https://www.ncbi.nlm.nih.gov/pubmed/28939395
http://dx.doi.org/10.1016/j.jim.2017.09.003