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Preformulation studies with the Escherichia coli double mutant heat-labile toxin adjuvant for use in an oral vaccine
Double mutant heat-labile toxin (dmLT) is a promising adjuvant for oral vaccine administration. The aims of our study were to develop sensitive methods to detect low concentrations of dmLT and to use the assays in preformulation studies to determine whether dmLT remains stable under conditions encou...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703769/ https://www.ncbi.nlm.nih.gov/pubmed/28939395 http://dx.doi.org/10.1016/j.jim.2017.09.003 |