Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway

Acetaminophen is a commonly used analgesic. However, an overdose of acetaminophen causes severe hepatotoxicity via depletion of hepatic glutathione. Here, we investigated the protective effects of sake lees hydrolysate against acetaminophen-induced hepatotoxicity in mice. Sake lees hydrolysate was a...

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Detalles Bibliográficos
Autores principales: Kawakami, Kayoko, Moritani, Chie, Uraji, Misugi, Fujita, Akiko, Kawakami, Koji, Hatanaka, Tadashi, Suzaki, Etsuko, Tsuboi, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703781/
https://www.ncbi.nlm.nih.gov/pubmed/29203962
http://dx.doi.org/10.3164/jcbn.17-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703781/
https://www.ncbi.nlm.nih.gov/pubmed/29203962
http://dx.doi.org/10.3164/jcbn.17-21

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