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Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway
Acetaminophen is a commonly used analgesic. However, an overdose of acetaminophen causes severe hepatotoxicity via depletion of hepatic glutathione. Here, we investigated the protective effects of sake lees hydrolysate against acetaminophen-induced hepatotoxicity in mice. Sake lees hydrolysate was a...
Autores principales: | Kawakami, Kayoko, Moritani, Chie, Uraji, Misugi, Fujita, Akiko, Kawakami, Koji, Hatanaka, Tadashi, Suzaki, Etsuko, Tsuboi, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703781/ https://www.ncbi.nlm.nih.gov/pubmed/29203962 http://dx.doi.org/10.3164/jcbn.17-21 |
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