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Stabilizers of edaravone aqueous solution and their action mechanisms. 2. Glutathione

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) has garnered attention since its approval for amyotrophic lateral sclerosis in Japan (2015) and the United States (2017). Edaravone is administered intravenously, and as such, is distributed in the form of an aqueous solution. However, aqueous solution...

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Detalles Bibliográficos
Autores principales: Tanaka, Masahiko, Motomiya, Satsuki, Fujisawa, Akio, Yamamoto, Yorihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703789/
https://www.ncbi.nlm.nih.gov/pubmed/29203956
http://dx.doi.org/10.3164/jcbn.17-75