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The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy

Cellular senescence describes an irreversible growth arrest characterized by distinct morphology, gene expression pattern, and secretory phenotype. The final or intermediate stages of senescence can be reached by different genetic mechanisms and in answer to different external and internal stresses....

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Detalles Bibliográficos
Autores principales: Schosserer, Markus, Grillari, Johannes, Breitenbach, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703792/
https://www.ncbi.nlm.nih.gov/pubmed/29218300
http://dx.doi.org/10.3389/fonc.2017.00278