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The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy
Cellular senescence describes an irreversible growth arrest characterized by distinct morphology, gene expression pattern, and secretory phenotype. The final or intermediate stages of senescence can be reached by different genetic mechanisms and in answer to different external and internal stresses....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703792/ https://www.ncbi.nlm.nih.gov/pubmed/29218300 http://dx.doi.org/10.3389/fonc.2017.00278 |