Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells

Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have analysed the...

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Detalles Bibliográficos
Autores principales: Spohrer, Sarah, Groß, Rebecca, Nalbach, Lisa, Schwind, Lisa, Stumpf, Heike, Menger, Michael D., Ampofo, Emmanuel, Montenarh, Mathias, Götz, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703852/
https://www.ncbi.nlm.nih.gov/pubmed/29180680
http://dx.doi.org/10.1038/s41598-017-16590-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703852/
https://www.ncbi.nlm.nih.gov/pubmed/29180680
http://dx.doi.org/10.1038/s41598-017-16590-0

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