Cargando…
Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells
Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have analysed the...
Autores principales: | Spohrer, Sarah, Groß, Rebecca, Nalbach, Lisa, Schwind, Lisa, Stumpf, Heike, Menger, Michael D., Ampofo, Emmanuel, Montenarh, Mathias, Götz, Claudia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703852/ https://www.ncbi.nlm.nih.gov/pubmed/29180680 http://dx.doi.org/10.1038/s41598-017-16590-0 |
Ejemplares similares
-
Protein Kinase CK2—A Putative Target for the Therapy of Diabetes Mellitus?
por: Ampofo, Emmanuel, et al.
Publicado: (2019) -
The Phosphorylation of PDX-1 by Protein Kinase CK2 Is Crucial for Its Stability
por: Klein, Sabrina, et al.
Publicado: (2016) -
Protein Kinase CK2 Controls Ca(V)2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-cells
por: Scheuer, Rebecca, et al.
Publicado: (2020) -
Inhibition of Protein Kinase CK2 Prevents Adipogenic Differentiation of Mesenchymal Stem Cells Like C3H/10T1/2 Cells
por: Schwind, Lisa, et al.
Publicado: (2017) -
Protein Kinase CK2 Contributes to Glucose Homeostasis by Targeting Fructose-1,6-Bisphosphatase 1
por: Pack, Mandy, et al.
Publicado: (2022)