Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats

Neonatal exposure to isoflurane can result in neuroapoptosis and persistent cognitive impairments. However, the underlying mechanisms remain elusive. Anaphase-promoting complex/cyclosome (APC/C) and its co-activator Cdh1 are E3 ubiquitin ligases that play important roles in the central nervous syste...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Wei, Kai, Hu, Rong, Zhang, Bo, Li, Li, Wan, Li, Zhang, Chuanhan, Yao, Wenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703863/
https://www.ncbi.nlm.nih.gov/pubmed/29218001
http://dx.doi.org/10.3389/fncel.2017.00368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703863/
https://www.ncbi.nlm.nih.gov/pubmed/29218001
http://dx.doi.org/10.3389/fncel.2017.00368

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