CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway

Many Crohn’s disease (CD) patients develop intestinal strictures, which are difficult to prevent and treat. Cationic steroid antimicrobial 13 (CSA13) shares cationic nature and antimicrobial function with antimicrobial peptide cathelicidin. As many functions of cathelicidin are mediated through form...

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Detalles Bibliográficos
Autores principales: Xu, Chunlan, Ghali, Sally, Wang, Jiani, Shih, David Q., Ortiz, Christina, Mussatto, Caroline C., Lee, Elaine C., Tran, Diana H., Jacobs, Jonathan P., Lagishetty, Venu, Fleshner, Phillip, Robbins, Lori, Vu, Michelle, Hing, Tressia C., McGovern, Dermot P. B, Koon, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703874/
https://www.ncbi.nlm.nih.gov/pubmed/29180648
http://dx.doi.org/10.1038/s41598-017-16753-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703874/
https://www.ncbi.nlm.nih.gov/pubmed/29180648
http://dx.doi.org/10.1038/s41598-017-16753-z

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