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Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance

Obesity-induced inflammation engenders insulin resistance and type 2 diabetes mellitus (T2DM) but the inflammatory effectors linking obesity to insulin resistance are incompletely understood. Here, we show that hepatic expression of Protein Tyrosine Phosphatase Receptor Gamma (PTPR-γ) is stimulated...

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Detalles Bibliográficos
Autores principales: Brenachot, Xavier, Ramadori, Giorgio, Ioris, Rafael M., Veyrat-Durebex, Christelle, Altirriba, Jordi, Aras, Ebru, Ljubicic, Sanda, Kohno, Daisuke, Fabbiano, Salvatore, Clement, Sophie, Goossens, Nicolas, Trajkovski, Mirko, Harroch, Sheila, Negro, Francesco, Coppari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703876/
https://www.ncbi.nlm.nih.gov/pubmed/29180649
http://dx.doi.org/10.1038/s41467-017-02074-2