The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

SUMO-targeted ubiquitin ligases (STUbLs) mediate the ubiquitylation of SUMOylated proteins to modulate their functions. In search of direct targets for the STUbL RNF4, we have developed TULIP (targets for ubiquitin ligases identified by proteomics) to covalently trap targets for ubiquitin E3 ligases...

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Detalles Bibliográficos
Autores principales: Kumar, Ramesh, González-Prieto, Román, Xiao, Zhenyu, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703878/
https://www.ncbi.nlm.nih.gov/pubmed/29180619
http://dx.doi.org/10.1038/s41467-017-01900-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703878/
https://www.ncbi.nlm.nih.gov/pubmed/29180619
http://dx.doi.org/10.1038/s41467-017-01900-x

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