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The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

Age-associated changes in chromatin structure have a major impact on organismal longevity. Despite being a central part of the ageing process, the organismal responses to the changes in chromatin organization remain unclear. Here we show that moderate disturbance of histone balance during C. elegans...

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Detalles Bibliográficos
Autores principales: Matilainen, Olli, Sleiman, Maroun S. Bou, Quiros, Pedro M., Garcia, Susana M. D. A., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703887/
https://www.ncbi.nlm.nih.gov/pubmed/29180639
http://dx.doi.org/10.1038/s41467-017-01903-8