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The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress
Age-associated changes in chromatin structure have a major impact on organismal longevity. Despite being a central part of the ageing process, the organismal responses to the changes in chromatin organization remain unclear. Here we show that moderate disturbance of histone balance during C. elegans...
Autores principales: | Matilainen, Olli, Sleiman, Maroun S. Bou, Quiros, Pedro M., Garcia, Susana M. D. A., Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703887/ https://www.ncbi.nlm.nih.gov/pubmed/29180639 http://dx.doi.org/10.1038/s41467-017-01903-8 |
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