Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer

Opposed to tubulin-binding agents, actin-binding small molecules have not yet become part of clinical tumor treatment, most likely due to the fear of general cytotoxicity. Addressing this problem, we investigated the long-term efficacy of sub-toxic doses of miuraenamide, an actin filament stabilizin...

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Detalles Bibliográficos
Autores principales: Moser, Christina, Rüdiger, Daniel, Förster, Florian, von Blume, Julia, Yu, Peng, Kuster, Bernhard, Kazmaier, Uli, Vollmar, Angelika M., Zahler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703899/
https://www.ncbi.nlm.nih.gov/pubmed/29180826
http://dx.doi.org/10.1038/s41598-017-16759-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703899/
https://www.ncbi.nlm.nih.gov/pubmed/29180826
http://dx.doi.org/10.1038/s41598-017-16759-7

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