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Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer
Opposed to tubulin-binding agents, actin-binding small molecules have not yet become part of clinical tumor treatment, most likely due to the fear of general cytotoxicity. Addressing this problem, we investigated the long-term efficacy of sub-toxic doses of miuraenamide, an actin filament stabilizin...
Autores principales: | Moser, Christina, Rüdiger, Daniel, Förster, Florian, von Blume, Julia, Yu, Peng, Kuster, Bernhard, Kazmaier, Uli, Vollmar, Angelika M., Zahler, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703899/ https://www.ncbi.nlm.nih.gov/pubmed/29180826 http://dx.doi.org/10.1038/s41598-017-16759-7 |
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