Cargando…
Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis
The underlying pathophysiology of liver dysfunction in urea cycle disorders (UCDs) is still largely elusive. There is some evidence that the accumulation of urea cycle (UC) intermediates are toxic for hepatocyte mitochondria. It is possible that liver injury is directly caused by the toxicity of amm...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Baishideng Publishing Group Inc
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703922/ https://www.ncbi.nlm.nih.gov/pubmed/29209134 http://dx.doi.org/10.3748/wjg.v23.i44.7930 |