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Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis

The underlying pathophysiology of liver dysfunction in urea cycle disorders (UCDs) is still largely elusive. There is some evidence that the accumulation of urea cycle (UC) intermediates are toxic for hepatocyte mitochondria. It is possible that liver injury is directly caused by the toxicity of amm...

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Detalles Bibliográficos
Autores principales:	Ivanovski, Ivan, Ješić, Miloš, Ivanovski, Ana, Garavelli, Livia, Ivanovski, Petar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703922/ https://www.ncbi.nlm.nih.gov/pubmed/29209134 http://dx.doi.org/10.3748/wjg.v23.i44.7930

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