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Palmitate induces fat accumulation by activating C/EBPβ-mediated G0S2 expression in HepG2 cells

AIM: To determine the role of G0/G1 switch gene 2 (G0S2) and its transcriptional regulation in palmitate-induced hepatic lipid accumulation. METHODS: HepG2 cells were treated with palmitate, or palmitate in combination with CCAAT/enhancer binding protein (C/EBP)β siRNA or G0S2 siRNA. The mRNA expres...

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Detalles Bibliográficos
Autores principales: Zhao, Nai-Qian, Li, Xiao-Yan, Wang, Li, Feng, Zi-Ling, Li, Xi-Fen, Wen, Yan-Fang, Han, Jin-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703930/
https://www.ncbi.nlm.nih.gov/pubmed/29209111
http://dx.doi.org/10.3748/wjg.v23.i43.7705