Cargando…
Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer’s disease drug candidates
SLM and SLOH, two analogues of carbazole-based cyanine compounds, have been shown to inhibit β-amyloid peptide aggregation in vitro and in Alzheimer’s disease model mice, which could be potentially developed into drugs for disease treatment. To pave the way for further pharmacokinetics-pharmacodynam...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703966/ https://www.ncbi.nlm.nih.gov/pubmed/29180684 http://dx.doi.org/10.1038/s41598-017-16635-4 |