Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport

Although α-synuclein (αSyn) has been linked to Parkinson’s disease (PD), the mechanisms underlying the causative role in PD remain unclear. We previously proposed a model for a transportable microtubule (tMT), in which dynein is anchored to a short tMT by LIS1 followed by the kinesin-dependent anter...

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Detalles Bibliográficos
Autores principales: Toba, Shiori, Jin, Mingyue, Yamada, Masami, Kumamoto, Kanako, Matsumoto, Sakiko, Yasunaga, Takuo, Fukunaga, Yuko, Miyazawa, Atsuo, Fujita, Sakiko, Itoh, Kyoko, Fushiki, Shinji, Kojima, Hiroaki, Wanibuchi, Hideki, Arai, Yoshiyuki, Nagai, Takeharu, Hirotsune, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703968/
https://www.ncbi.nlm.nih.gov/pubmed/29180624
http://dx.doi.org/10.1038/s41598-017-15575-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703968/
https://www.ncbi.nlm.nih.gov/pubmed/29180624
http://dx.doi.org/10.1038/s41598-017-15575-3

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