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MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication

Enterovirus 71 (EV71) is the predominant causative pathogen of hand-foot-and-mouth disease (HFMD). Contrary to other HFMD-causing enterovirus, EV71 can lead to severe neurological complications, even death. MicroRNAs (miRNAs) are small non-coding RNAs that constitute the largest family of gene regul...

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Detalles Bibliográficos
Autores principales: Zheng, Caishang, Zheng, Zhenhua, Sun, Jianhong, Zhang, Yuan, Wei, Chunyu, Ke, Xianliang, Liu, Yan, Deng, Li, Wang, Hanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703983/
https://www.ncbi.nlm.nih.gov/pubmed/29180670
http://dx.doi.org/10.1038/s41598-017-16616-7