Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics

Nearly all studies of angiogenesis have focused on uni-family ligand-receptor binding, e.g., VEGFs bind to VEGF receptors, PDGFs bind to PDGF receptors, etc. The discovery of VEGF-PDGFRs binding challenges this paradigm and calls for investigation of other ligand-receptor binding possibilities. We u...

Descripción completa

Detalles Bibliográficos
Autores principales: Mamer, Spencer B., Chen, Si, Weddell, Jared C., Palasz, Alexandra, Wittenkeller, Ashley, Kumar, Manu, Imoukhuede, P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704011/
https://www.ncbi.nlm.nih.gov/pubmed/29180757
http://dx.doi.org/10.1038/s41598-017-16610-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704011/
https://www.ncbi.nlm.nih.gov/pubmed/29180757
http://dx.doi.org/10.1038/s41598-017-16610-z

Ejemplares similares