d-Ribose as a Contributor to Glycated Haemoglobin

Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c. Using mass spectrometry, we detected glycation of haemoglobin with d-ribose produces 10 carboxylmethyllysines (CMLs). The first-order...

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Detalles Bibliográficos
Autores principales: Chen, Xixi, Su, Tao, Chen, Yao, He, Yingge, Liu, Ying, Xu, Yong, Wei, Yan, Li, Juan, He, Rongqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704047/
https://www.ncbi.nlm.nih.gov/pubmed/29033370
http://dx.doi.org/10.1016/j.ebiom.2017.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704047/
https://www.ncbi.nlm.nih.gov/pubmed/29033370
http://dx.doi.org/10.1016/j.ebiom.2017.10.001

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