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A DNA Vaccine Protects Human Immune Cells against Zika Virus Infection in Humanized Mice

A DNA vaccine encoding prM and E protein has been shown to induce protection against Zika virus (ZIKV) infection in mice and monkeys. However, its effectiveness in humans remains undefined. Moreover, identification of which immune cell types are specifically infected in humans is unclear. We show th...

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Detalles Bibliográficos
Autores principales: Yi, Guohua, Xu, Xuequn, Abraham, Sojan, Petersen, Sean, Guo, Hua, Ortega, Nora, Shankar, Premlata, Manjunath, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704055/
https://www.ncbi.nlm.nih.gov/pubmed/29033368
http://dx.doi.org/10.1016/j.ebiom.2017.10.006