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A DNA Vaccine Protects Human Immune Cells against Zika Virus Infection in Humanized Mice
A DNA vaccine encoding prM and E protein has been shown to induce protection against Zika virus (ZIKV) infection in mice and monkeys. However, its effectiveness in humans remains undefined. Moreover, identification of which immune cell types are specifically infected in humans is unclear. We show th...
Autores principales: | Yi, Guohua, Xu, Xuequn, Abraham, Sojan, Petersen, Sean, Guo, Hua, Ortega, Nora, Shankar, Premlata, Manjunath, N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704055/ https://www.ncbi.nlm.nih.gov/pubmed/29033368 http://dx.doi.org/10.1016/j.ebiom.2017.10.006 |
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