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Dual Mechanisms for Balancing Th17 and Treg Cell Fate by CREB

Th17 cells, which express the cytokine IL-17A, and master regulator RORγt, are important in the inflammatory response to fungal and bacterial pathogens, but also have a pathogenic role in many inflammatory disorders. In contrast, regulatory T cells (Treg), expressing the Foxp3 transcription factor,...

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Detalles Bibliográficos
Autores principales: Symons, Antony, Ouyang, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704069/
https://www.ncbi.nlm.nih.gov/pubmed/29129697
http://dx.doi.org/10.1016/j.ebiom.2017.10.031