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Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease

Oxidative stress arises when cellular antioxidant defences become overwhelmed by a surplus generation of reactive oxygen species (ROS). Once this occurs, many cellular biomolecules such as DNA, lipids, and proteins become susceptible to free radical-induced oxidative damage, and this may consequentl...

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Detalles Bibliográficos
Autores principales: Al Shahrani, Mesfer, Heales, Simon, Hargreaves, Iain, Orford, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704117/
https://www.ncbi.nlm.nih.gov/pubmed/29077060
http://dx.doi.org/10.3390/jcm6110100