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Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer

Cancer is a devastating disease that claims over 8 million lives each year. Understanding the molecular etiology of the disease is critical to identify and develop new therapeutic strategies and targets. Chromosome instability (CIN) is an abnormal phenotype, characterized by progressive numerical an...

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Detalles Bibliográficos
Autores principales: Thompson, Laura L., Jeusset, Lucile M-P., Lepage, Chloe C., McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704169/
https://www.ncbi.nlm.nih.gov/pubmed/29104272
http://dx.doi.org/10.3390/cancers9110151