Modulating cellular balance of Rps3 mono-ubiquitination by both Hel2 E3 ligase and Ubp3 deubiquitinase regulates protein quality control

When a ribosome complex is stalled during the translation elongation process in eukaryotes, the mono-ubiquitination of Rps3 has recently been shown to be critical to ribosome quality control. We have discovered that the regulatory role of Rps3 mono-ubiquitination is controlled by a deubiquitinase. W...

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Detalles Bibliográficos
Autores principales: Jung, Youjin, Kim, Hag Dong, Yang, Hee Woong, Kim, Hye Jin, Jang, Chang-Young, Kim, Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704183/
https://www.ncbi.nlm.nih.gov/pubmed/29147007
http://dx.doi.org/10.1038/emm.2017.128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704183/
https://www.ncbi.nlm.nih.gov/pubmed/29147007
http://dx.doi.org/10.1038/emm.2017.128

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