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The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery

Naive CD4 T cells activated by antigen-presenting cells (APCs) undergo terminal differentiation in the periphery. Multiple mechanisms determine their fates, that is, whether they differentiate into conventional T (Tconv) cells or regulatory T (Treg) cells. The key event during Treg generation is exp...

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Detalles Bibliográficos
Autores principales: Lee, Wonyong, Kim, Hyeong Su, Hwang, Soo Seok, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704186/
https://www.ncbi.nlm.nih.gov/pubmed/29147008
http://dx.doi.org/10.1038/emm.2017.157