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The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery
Naive CD4 T cells activated by antigen-presenting cells (APCs) undergo terminal differentiation in the periphery. Multiple mechanisms determine their fates, that is, whether they differentiate into conventional T (Tconv) cells or regulatory T (Treg) cells. The key event during Treg generation is exp...
Autores principales: | Lee, Wonyong, Kim, Hyeong Su, Hwang, Soo Seok, Lee, Gap Ryol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704186/ https://www.ncbi.nlm.nih.gov/pubmed/29147008 http://dx.doi.org/10.1038/emm.2017.157 |
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