Leukotriene B(4) receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation

Recently, single-nucleotide polymorphisms (SNPs) in G-protein-coupled receptors (GPCRs) have been suggested to contribute to physiopathology and therapeutic effects. Leukotriene B(4) receptor 2 (BLT2), a member of the GPCR family, plays a critical role in the pathogenesis of several inflammatory dis...

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Detalles Bibliográficos
Autores principales: Jang, Jae-Hyun, Wei, Jun-Dong, Kim, Minsup, Kim, Joo-Young, Cho, Art E, Kim, Jae-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704194/
https://www.ncbi.nlm.nih.gov/pubmed/29170475
http://dx.doi.org/10.1038/emm.2017.192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704194/
https://www.ncbi.nlm.nih.gov/pubmed/29170475
http://dx.doi.org/10.1038/emm.2017.192

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