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Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases

Tissue fibrosis, characterized by excessive accumulation of aberrant extracellular matrix (ECM) produced by myofibroblasts, is a growing cause of mortality worldwide. Understanding the factors that induce myofibroblastic differentiation is paramount to prevent or reverse the fibrogenic process. Inte...

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Detalles Bibliográficos
Autores principales: Bansal, Ruchi, Nakagawa, Shigeki, Yazdani, Saleh, van Baarlen, Joop, Venkatesh, Anu, Koh, Anna P, Song, Won-Min, Goossens, Nicolas, Watanabe, Hideo, Beasley, Mary B, Powell, Charles A, Storm, Gert, Kaminski, Naftali, van Goor, Harry, Friedman, Scott L, Hoshida, Yujin, Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704196/
https://www.ncbi.nlm.nih.gov/pubmed/29147013
http://dx.doi.org/10.1038/emm.2017.213